Key Features

• Macrocyclic + Ionic Stability: Rigid DOTA ring and ionic charge create one of the most stable Gd complexes available, minimising transmetallation and gadolinium release.
• Approved for All Ages & Multiple Indications: Licensed for contrast enhancement in cranial, spinal and whole body MRI—including cardiac, breast, uterine and paediatric imaging—and for MR angiography.
• Proven Safety Record: > 100 million patient doses worldwide; extremely low incidence of NSF and hypersensitivity reactions.
• Consistent, High Quality Images: Optimised T₁ relaxivity highlights lesions, vasculature and soft tissue anatomy with excellent grey/white matter differentiation.
• Renal & Hepatic Friendly Dosing: Standard single dose (0.1 mmol kg⁻¹) requires no adjustment in mild to severe renal or hepatic impairment* and clears primarily by glomerular filtration. *Use standard GBCA precautions in end stage renal disease; schedule post dose dialysis when applicable.
• Flexible Presentations: 10 mL, 15 mL and 20 mL single dose vials or prefilled syringes support paediatric, adult and high BMI studies without overfill wastage.

Why Choose Dotarem®?

• Maximum gadolinium chelation stability: for greater patient safety.
• Versatile clinical utility: one formulation covers CNS, body, vascular and paediatric MRI.
• Simple weight based dosing: with no dilution or reconstruction steps.
• Extensive global experience: over 30 years supports confident routine and high risk imaging.
• Single use packaging: reduces contamination risk and streamlines pharmacy workflow.

Dotarem® offers radiology teams a dependable, easy to administer MRI contrast agent that marries best in class molecular stability with broad clinical versatility—helping deliver crisp, diagnostic images while prioritising patient safety.